Industries with low-temperature heat demand, such as laundry and syrup sectors, heavily rely on natural gas-fired boilers, posing challenges to achieving net-zero emissions by 2050. Like hard-to-abate sectors, they must explore energy transition strategies, including heat recovery, fuel substitution, or carbon capture, to reduce CO2 emissions. This paper evaluates the potential of energy transition in these sectors through case studies, using a mixed integer linear programming (MILP) approach. The analysis focuses on three key performance indicators (KPIs): specific energy consumption, CO2 reduction, and variable costs. By 2050, the adoption of heat pumps and waste valorization emerge as the most promising solutions for the syrup and laundry sectors. Specifically, the use of heat pumps reduces energy demand by at least 50%, while on-site biofuel production can fully replace natural gas consumption, thus eliminating dependency on external energy sources. The analysis highlights the importance of sector-specific strategies to meet climate targets, offering a pathway for low-temperature heat industries to reduce emissions while addressing economic and technological constraints.