research article

Comment on "Circadian rhythms in the absence of the clock gene Bmal1"

Abruzzi, Katharine C.
•
Gobet, Cedric  
•
Naef, Felix  
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April 16, 2021
Science

Ray et al. (Reports, 14 February 2020, p. 800) recently claimed temperature-compensated, free-running mRNA oscillations in Bmal1(-/-) liver slices and skin fibroblasts. We reanalyzed these data and found far fewer reproducible mRNA oscillations in this genotype. We also note errors and potentially inappropriate analyses.

Type
research article
DOI
10.1126/science.abf0922
Web of Science ID

WOS:000641286700002

Author(s)
Abruzzi, Katharine C.
Gobet, Cedric  
Naef, Felix  
Rosbash, Michael
Date Issued

2021-04-16

Publisher

American Association for the Advancement of Science

Published in
Science
Volume

372

Issue

6539

Article Number

eabf0922

Subjects

Multidisciplinary Sciences

•

Science & Technology - Other Topics

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
UPNAE  
Available on Infoscience
June 5, 2021
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/178547