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  4. Physics-Informed Joint Multi-TE Super-Resolution with Implicit Neural Representation for Robust Fetal T2 Mapping
 
conference paper

Physics-Informed Joint Multi-TE Super-Resolution with Implicit Neural Representation for Robust Fetal T2 Mapping

Bulut, Busra  
•
Dannecker, Maik
•
Sanchez, Thomas  
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Link-Sourani, Daphna
•
Abaci Turk, Esra
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2026
Perinatal, Preterm and Paediatric Image Analysis. 10th International Workshop, PIPPI 2025, Held in Conjunction with MICCAI 2025, Daejeon, South Korea, September 27, 2025, Proceedings
10th International Workshop on Preterm, Perinatal and Paediatric Image Analysis

T2 mapping in fetal brain MRI has the potential to improve characterization of the developing brain, especially at mid-field (0.55T), where T2 decay is slower. However, this is challenging as fetal MRI acquisition relies on multiple motion-corrupted stacks of thick slices, requiring slice-to-volume reconstruction (SVR) to estimate a high-resolution (HR) 3D volume. Currently, T2 mapping involves repeated acquisitions of these stacks at each echo time (TE), leading to long scan times and high sensitivity to motion. We tackle this challenge with a method that jointly reconstructs data across TEs, addressing severe motion. Our approach combines implicit neural representations with a physics-informed regularization that models T2 decay, enabling information sharing across TEs while preserving anatomical and quantitative T2 fidelity. We demonstrate state-of-the-art performance on simulated fetal brain and in vivo adult datasets with fetal-like motion. We also present the first in vivo fetal T2 mapping results at 0.55T. Our study shows potential for reducing the number of stacks per TE in T2 mapping by leveraging anatomical redundancy.

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Type
conference paper
DOI
10.1007/978-3-032-05997-0_6
Scopus ID

2-s2.0-105018304137

Author(s)
Bulut, Busra  

École Polytechnique Fédérale de Lausanne

Dannecker, Maik

Technische Universität München

Sanchez, Thomas  

École Polytechnique Fédérale de Lausanne

Neves Silva, Sara

King's College London

Zalevskyi, Vladyslav  

École Polytechnique Fédérale de Lausanne

Jia, Steven

Institut de Neurosciences de la Timone

Ledoux, Jean Baptiste

École Polytechnique Fédérale de Lausanne

Auzias, Guillaume

Institut de Neurosciences de la Timone

Rousseau, François

Laboratoire de Traitement de l'Information Médicale (Latim)

Hutter, Jana

Imperial College London

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Editors
Link-Sourani, Daphna
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Abaci Turk, Esra
•
Bastiaansen, Wietske
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Hutter, Jana
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Melbourne, Andrew
•
Licandro, Roxane
Date Issued

2026

Publisher

Springer Science and Business Media Deutschland GmbH

Published in
Perinatal, Preterm and Paediatric Image Analysis. 10th International Workshop, PIPPI 2025, Held in Conjunction with MICCAI 2025, Daejeon, South Korea, September 27, 2025, Proceedings
DOI of the book
https://doi.org/10.1007/978-3-032-05997-0
ISBN of the book

978-3-032-05996-3

978-3-032-05997-0

Series title/Series vol.

Lecture Notes in Computer Science; 16118 LNCS

ISSN (of the series)

1611-3349

0302-9743

Start page

61

End page

72

Subjects

Implicit Neural Representation

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Quantitative mapping

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Slice-to-volume reconstruction

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
LTS5  
CIBM  
Event nameEvent acronymEvent placeEvent date
10th International Workshop on Preterm, Perinatal and Paediatric Image Analysis

Daejeon, Korea, Republic of

2025-09-27 - 2025-09-27

FunderFunding(s)Grant NumberGrant URL

Swiss National Science Foundation

215641

ERC

Deep4MI-884622,MULTI-FACT-8810003808

Available on Infoscience
October 20, 2025
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/255105
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