research article
Ruthenium(II)–arene and triruthenium-carbonyl cluster complexes with new water-soluble phopsphites based on glucose: Synthesis, characterization and antiproliferative activity
May 5, 2020
New water-soluble 3,5,6-bicyclophosphite ligands based on glucose modified with uracil, 5-fluorouracil or thymine are reported. The phosphite ligands were subsequently reacted with bis[dichlorido(η6-p-cymene)ruthenium(II)] and trirutheniumdodecacarbonyl to afford monoruthenium analogues of RAPTA-C and triruthenium clusters with 1–3 phosphite ligands, respectively. The influence of ligands on the stability of the compounds and the antiproliferative activity of the compounds was investigated.
Type
research article
Author(s)
Gonchar, Maria R.
Matnurov, Egor M.
Burdina, Tatiana A.
Zava, Oliver
Ridel, Tina
Milaeva, Elena R.
Nazarov, Alexey A.
Date Issued
2020-05-05
Published in
Volume
919
Article Number
121312
Editorial or Peer reviewed
REVIEWED
Written at
EPFL
EPFL units
Available on Infoscience
July 9, 2020
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