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review article

Mechanisms of asymmetric cell division: flies and worms pave the way

Gönczy, Pierre  
2008
Nature reviews. Molecular cell biology

Asymmetric cell division is fundamental for generating diversity in multicellular organisms. The mechanisms that govern asymmetric cell division are increasingly well understood, owing notably to studies that were conducted in Drosophila melanogaster and Caenorhabditis elegans. Lessons learned from these two model organisms also apply to cells that divide asymmetrically in other metazoans, such as self-renewing stem cells in mammals

  • Details
  • Metrics
Type
review article
DOI
10.1038/nrm2388
Web of Science ID

WOS:000255265300011

Author(s)
Gönczy, Pierre  
Date Issued

2008

Published in
Nature reviews. Molecular cell biology
Volume

9

Issue

5

Start page

355

End page

366

Subjects

Animals

•

Caenorhabditis elegans/cytology

•

Cell Cycle Proteins/metabolism

•

Cell Division/physiology

•

Cell Polarity

•

Centrosome/metabolism

•

Drosophila Proteins/genetics/metabolism

•

Drosophila melanogaster/cytology

•

Embryo

•

Nonmammalian/cytology/physiology

•

GTP-Binding Protein alpha Subunits/metabolism

•

Helminth Proteins/genetics/metabolism

•

Juvenile Hormones/genetics/metabolism

•

Mitotic Spindle Apparatus/metabolism/ultrastructure

•

Protein Folding

•

Receptors

•

Notch/genetics/metabolism

•

Signal Transduction/physiology

•

Ubiquitin-Protein Ligases/genetics/metabolism

Note

Author address: Swiss Institute for Experimental Cancer Research (ISREC), Swiss Federal Institute of Technology (EPFL), School of Life Sciences, Lausanne, Switzerland

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
UPGON  
Available on Infoscience
August 31, 2008
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/27669
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