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research article
Deep UV generation and direct DNA photo-interaction by harmonic nanoparticles in labelled samples
2014
A biophotonics approach based on the nonlinear optical process of second harmonic generation is presented and demonstrated on malignant human cell lines labelled by harmonic nanoparticles. The method enables independent imaging and therapeutic action, selecting each modality by simply tuning the excitation laser wavelength from infrared to visible. In particular, the generation of deep ultraviolet radiation at 270 nm allows direct interaction with nuclear DNA in the absence of photosensitizing molecules.
Use this identifier to reference this record
Type
research article
Web of Science ID
WOS:000332127200056
Authors
•
Magouroux, Thibaud
•
•
Schwung, Sebastian
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Dubled, Marc
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Schneiter, Guillaume Stephane
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Rytz, Daniel
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Bonacina, Luigi
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Wolf, Jean-Pierre
Publication date
2014
Publisher
Published in
Volume
6
Issue
5
Start page
2929
End page
2936
Peer reviewed
REVIEWED
EPFL units
Available on Infoscience
April 2, 2014