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research article

A patient-specific aortic valve model based on moving resistive immersed implicit surfaces

Fedele, Marco
•
Faggiano, Elena
•
Dede, Luca
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2017
Biomechanics And Modeling In Mechanobiology

In this paper, we propose a full computational framework to simulate the hemodynamics in the aorta including the valve. Closed and open valve surfaces, as well as the lumen aorta, are reconstructed directly from medical images using new ad hoc algorithms, allowing a patient-specific simulation. The fluid dynamics problem that accounts from the movement of the valve is solved by a new 3D-0D fluid-structure interaction model in which the valve surface is implicitly represented through level set functions, yielding, in the Navier-Stokes equations, a resistive penalization term enforcing the blood to adhere to the valve leaflets. The dynamics of the valve between its closed and open position is modeled using a reduced geometric 0D model. At the discrete level, a finite element formulation is used and the SUPG stabilization is extended to include the resistive term in the Navier-Stokes equations. Then, after time discretization, the 3D fluid and 0D valve models are coupled through a staggered approach. This computational framework, applied to a patient-specific geometry and data, allows to simulate the movement of the valve, the sharp pressure jump occurring across the leaflets, and the blood flow pattern inside the aorta.

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Type
research article
DOI
10.1007/s10237-017-0919-1
Web of Science ID

WOS:000410757300019

Author(s)
Fedele, Marco
Faggiano, Elena
Dede, Luca
Quarteroni, Alfio
Date Issued

2017

Publisher

Springer Heidelberg

Published in
Biomechanics And Modeling In Mechanobiology
Volume

16

Issue

5

Start page

1779

End page

1803

Subjects

Aortic valve

•

Image-based modeling

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Patient-specific simulation

•

Computational fluid dynamics

•

Finite element method

•

Heart modeling

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
CMCS  
Available on Infoscience
October 9, 2017
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/141160
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