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  4. Thermostable phospholipase C: A key to efficient and sustainable enzymatic oil degumming processes
 
review article

Thermostable phospholipase C: A key to efficient and sustainable enzymatic oil degumming processes

Val, Diego S.
•
Nardo, Luisina Di
•
Marchisio, Fiorela
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2025
JAOCS, Journal of the American Oil Chemists' Society

Phospholipase C (PLC) enzymes play a pivotal role in the degumming process of edible oils, which is essential for producing high-quality refined oils. The enzymatic degumming process, compared with conventional chemical methods, offers significant advantages including improved oil yield, reduced environmental impact, and lower operational costs. However, the industrial application of PLC enzymes is often hindered by their limited stability under harsh processing conditions. This has driven extensive research efforts toward engineering thermostable PLC variants that can withstand the high temperatures and harsh environments typical of oil refining processes. In this review, we explore the latest advancements in the application, design and optimization of thermostable PLC enzymes. We discuss the fundamental economic and ecological interest behind the goal of obtaining thermostable enzymes, and two approaches to the problem, namely the search for enzymes in thermophilic organisms and the design of new sequences with improved stability and activity parameters.

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Type
review article
DOI
10.1002/aocs.12934
Scopus ID

2-s2.0-85215692458

Author(s)
Val, Diego S.
•
Nardo, Luisina Di
•
Marchisio, Fiorela
•
Lacava, Franco
•
Aguirre, Andrés
•
Peiru, Salvador
•
Castelli, María Eugenia
•
Espariz, Martín
•
Abriata, Luciano A.  
•
Menzella, Hugo G.
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Date Issued

2025

Published in
JAOCS, Journal of the American Oil Chemists' Society
Subjects

biotechnology biocatalysis

•

enzymology

•

extraction

•

fermentation

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lipids

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phospholipids

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processing technology

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
UPDALPE  
Available on Infoscience
January 30, 2025
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/246047
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