research article
Enantioselective C-C bond activation of allenyl cyclobutanes: access to cyclohexenones with quaternary stereogenic centers
Chiral rhodium(I) complexes activate allenyl tert-cyclobutanols efficiently through enantioselective insertion into a C-C σ bond of the cyclobutane. Ring expansion by this method produced cyclohexenones with quaternary stereogenic centers with excellent enantioselectivity. The catalyst loading can be decreased to just 0.1 mol% in rhodium.
Type
research article
Author(s)
Seiser, Tobias
Date Issued
2008
Publisher
Published in
Volume
47
Start page
9294
End page
9297
Note
CAPLUS AN 2008:1483761(Journal)
Editorial or Peer reviewed
REVIEWED
Written at
OTHER
EPFL units
Available on Infoscience
August 17, 2011
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