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patent

Neuromodulation/neurostimulation system for restoring a motor function and facilitating neurological recovery

Lorach, Henri  
•
Galvez-Solano, Andrea
•
Courtine, Grègoire  
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2024

The present invention relates to a neuromodulation/neurostimulation system (100) for restoring a motor function of the upper and/or lower limbs and facilitating neurological recovery in a patient (P) with spinal cord injury (SCI) and/or other neurological disorders, said system (100) comprising: a processing unit (10), which is configured and adapted provide stimulation commands; an implantable or external stimulation unit (12), which is configured and adapted to deliver neuromodulation therapy, in particular epidural electrical stimulation (EES) to the dorsal roots of the spinal cord (SC) of said patient (P); at least one implantable or external pulse generator (14), operatively connected to the stimulation unit (12); an implantable neurosensor (16) including electronic components that are configured and adapted to detect electrocorticographic (ECoG) signals from the sensorimotor cortex (C) of said patient (P), denoting a motor intention of said patient (P), wherein the processing unit (10), the stimulation unit (12) and the implantable neurosensor (16) are operatively connected to define a brain-spinal interface (BSI), and wherein the processing unit (10) is configured and adapted to: collect and decode, preferably in real-time, the ECoG signals from the sensorimotor cortex (C) into a corresponding motor intention of said patient (P); converting, preferably in real-time, the decoded motor intentions into corresponding stimulation commands, and forwarding, preferably in real-time, the stimulation command to the at least one pulse generator (14).

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Type
patent
EPO Family ID

86282246

Author(s)
Lorach, Henri  
Galvez-Solano, Andrea
Courtine, Grègoire  
Bloch, Jocelyne  
Charvet, Guillaume
Sauter-Starace, Fabien
Aksenova, Tetiana
Issuers

École Polytechnique Fédérale de Lausanne

Note

Alternative title(s) : (fr) Système de neuromodulation/neurostimulation pour restaurer une fonction motrice et faciliter la récupération neurologique

EPFL units
AVP-R-TTO  
IdentifierCountry codeKind codeDate issued

WO2024223898

WO

A1

2024-10-31

Available on Infoscience
February 3, 2025
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/246415
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