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  4. Particle Imaging Velocimetry Evaluation of Intracranial Stents in Sidewall Aneurysm: Hemodynamic Transition Related to the Stent Design
 
research article

Particle Imaging Velocimetry Evaluation of Intracranial Stents in Sidewall Aneurysm: Hemodynamic Transition Related to the Stent Design

Bouillot, Pierre
•
Brina, Olivier
•
Ouared, Rafik
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2014
Plos One

We investigated the flow modifications induced by a large panel of commercial-off-the-shelf (COTS) intracranial stents in an idealized sidewall intracranial aneurysm (IA). Flow velocities in IA silicone model were assessed with and without stent implantation using particle imaging velocimetry (PIV). The use of the recently developed multi-time-lag method has allowed for uniform and precise measurements of both high and low velocities at IA neck and dome, respectively. Flow modification analysis of both regular (RSs) and flow diverter stents (FDSs) was subsequently correlated with relevant geometrical stent parameters. Flow reduction was found to be highly sensitive to stent porosity variations for regular stents RSs and moderately sensitive for FDSs. Consequently, two distinct IA flow change trends, with velocity reductions up to 50% and 90%, were identified for high-porosity RS and low-porosity FDS, respectively. The intermediate porosity (88%) regular braided stent provided the limit at which the transition in flow change trend occurred with a flow reduction of 84%. This transition occurred with decreasing stent porosity, as the driving force in IA neck changed from shear stress to differential pressure. Therefore, these results suggest that stents with intermediate porosities could possibly provide similar flow change patterns to FDS, favourable to curative thrombogenesis in IAs.

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Type
research article
DOI
10.1371/journal.pone.0113762
Web of Science ID

WOS:000349128700043

Author(s)
Bouillot, Pierre
Brina, Olivier
Ouared, Rafik
Lovblad, Karl-Olof
Farhat, Mohamed  
Pereira, Vitor Mendes
Date Issued

2014

Publisher

Public Library of Science

Published in
Plos One
Volume

9

Issue

12

Article Number

e113762

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
LMH  
Available on Infoscience
April 13, 2015
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/113128
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