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  4. Load-bearing hydrogels ionically reinforced through competitive ligand exchanges
 
research article

Load-bearing hydrogels ionically reinforced through competitive ligand exchanges

Hirsch, Matteo  
•
Steinacher, Mathias  
•
Zhao, Ran  
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August 31, 2021
Biomaterials Science

Fast advances in soft robotics and tissue engineering demand for new soft materials whose mechanical properties can be interchangeably and locally varied, thereby enabling, for example, the design of soft joints within an integral material. Inspired by nature, we introduce a competitive ligand-mediated approach to selectively and interchangeably reinforce metal-coordinated hydrogels. This is achieved by reinforcing carboxylate-containing hydrogels with Fe3+ ions. Key to achieving a homogeneous, predictable reinforcement of the hydrogels is the presence of weak complexation agents that delay the formation of metal-complexes within the hydrogels, thereby allowing a homogeneous distribution of the metal ions. The resulting metal-reinforced hydrogels show a compressive modulus of up to 2.5 MPa, while being able to withstand pressures as high as 0.6 MPa without appreciable damage. Competitive ligand exchanges offer an additional advantage: they enable non-linear compositional changes that, for example, allow the formation of joints within these hydrogels. These features open up new possibilities to extend the field of use of metal reinforced hydrogels to load-bearing applications that are omnipresent for example in soft robots and actuators.

  • Details
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Type
research article
DOI
10.1039/d1bm01170g
Web of Science ID

WOS:000694023900001

Author(s)
Hirsch, Matteo  
Steinacher, Mathias  
Zhao, Ran  
Amstad, Esther  
Date Issued

2021-08-31

Publisher

ROYAL SOC CHEMISTRY

Published in
Biomaterials Science
Volume

9

Issue

20

Start page

6753

End page

6762

Subjects

Materials Science, Biomaterials

•

Materials Science

•

double-network hydrogels

•

coordination

•

elastomers

•

toughness

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
SMAL  
Available on Infoscience
September 25, 2021
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/181614
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