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  4. Development of an in situ controllable polymerization tool and process for hydrogel used to replace nucleus pulposus
 
conference paper

Development of an in situ controllable polymerization tool and process for hydrogel used to replace nucleus pulposus

Schmocker, Andreas M.  
•
Khoushabi, Azadeh  
•
Bourban, Pierre-Etienne  
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Kurachi, C
•
Svanberg, K
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2015
Biophotonics South America
Joint Meeting of the 1st SPIE Conference on Biophotonics South America (BSA) / 15th World Congress of the International-Photodynamic-Association (IPA)

Currently implants or tissue replacements are inserted either as a whole implant or by injecting a liquid which polymerizes to form a solid implant at the appropriate location. This is either highly invasive or not controllable. We developed a tool to perform such surgeries in a minimally invasive and controllable way. It combines photopolymerization and fluorescence spectroscopy in a surgical apparatus. However, to successfully replace tissue such as cartilage or an intervertebral disc, photopolymerizable materials do not only need to be photoactive. They should also be able to withstand the environmental loading conditions after implantation. Therefore we developed a set of in situ and in vitro tests adapted to the evaluation of photopolymerized tissue replacements and implants. In particular in this article, we report on a method, which combines photopolymerization and photorheology to track the current state of polymer during photopolymerization.

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Type
conference paper
DOI
10.1117/12.2180457
Web of Science ID

WOS:000359467600015

Author(s)
Schmocker, Andreas M.  
Khoushabi, Azadeh  
Bourban, Pierre-Etienne  
Schizas, Constantin
Pioletti, Dominique P.  
Moser, Christophe  
Editors
Kurachi, C
•
Svanberg, K
•
Tromberg, Bj
•
Bagnato, Vs
Date Issued

2015

Publisher

Spie-Int Soc Optical Engineering

Publisher place

Bellingham

Published in
Biophotonics South America
ISBN of the book

978-1-62841-696-1

Total of pages

9

Series title/Series vol.

Proceedings of SPIE

Volume

9531

Start page

953115

Subjects

Polymerized medical implant

•

light scattering

•

cross-linking

•

injectable hydrogel

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in situ photopolymerization

•

intervertebral disc regeneration

•

nucleus pulpous replacement

•

fluorescence monitoring

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
LAPD  
LBO  
Event nameEvent placeEvent date
Joint Meeting of the 1st SPIE Conference on Biophotonics South America (BSA) / 15th World Congress of the International-Photodynamic-Association (IPA)

Rio de Janeiro, BRAZIL

MAY 23-25, 2015

Available on Infoscience
September 28, 2015
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/119070
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