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  4. Occupational risk of SARS-CoV-2 infection and reinfection during the second pandemic surge: a cohort study
 
research article

Occupational risk of SARS-CoV-2 infection and reinfection during the second pandemic surge: a cohort study

Leidi, Antonio
•
Berner, Amandine
•
Dumont, Roxane
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2022
Occupational And Environmental Medicine

Objectives This cohort study including essential workers, assessed the risk and incidence of SARS-CoV-2 infection during the second surge of COVID-19 according to baseline serostatus and occupational sector. Methods Essential workers were selected from a seroprevalence survey cohort in Geneva, Switzerland and were linked to a state centralised registry compiling SARS-CoV-2 infections. Primary outcome was the incidence of virologically confirmed infections from serological assessment (between May and September 2020) to 25 January 2021, according to baseline antibody status and stratified by three predefined occupational groups (occupations requiring sustained physical proximity, involving brief regular contact or others). Results 10 457 essential workers were included (occupations requiring sustained physical proximity accounted for 3057 individuals, those involving regular brief contact, 3645 and 3755 workers were classified under 'Other essential occupations'). After a follow-up period of over 27 weeks, 5 (0.6%) seropositive and 830 (8.5%) seronegative individuals had a positive SARS-CoV-2 test, with an incidence rate of 0.2 (95% CI 0.1 to 0.6) and 3.2 (95% CI 2.9 to 3.4) cases per person-week, respectively. Incidences were similar across occupational groups. Seropositive essential workers had a 93% reduction in the hazard (HR of 0.07, 95% CI 0.03 to 0.17) of having a positive test during the follow-up with no significant between-occupational group difference. Conclusions A 10-fold reduction in the hazard of being virologically tested positive was observed among anti-SARS-CoV-2 seropositive essential workers regardless of their sector of occupation, confirming the seroprotective effect of a previous SARS-CoV2 exposure at least 6 months after infection.

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Type
research article
DOI
10.1136/oemed-2021-107924
Web of Science ID

WOS:000728861100001

Author(s)
Leidi, Antonio
Berner, Amandine
Dumont, Roxane
Dubos, Richard
Koegler, Flora
Piumatti, Giovanni
Vuilleumier, Nicolas
Kaiser, Laurent
Balavoine, Jean-Francois
Trono, Didier  
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Date Issued

2022

Publisher

BMJ PUBLISHING GROUP

Published in
Occupational And Environmental Medicine
Volume

79

Start page

116

End page

119

Subjects

Public, Environmental & Occupational Health

•

covid-19

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occupational health

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
LVG  
Available on Infoscience
December 18, 2021
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/183960
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