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research article

Solvability analysis and numerical approximation of linearized cardiac electromechanics

Andreianov, Boris
•
Bendahmane, Mostafa
•
Quarteroni, Alfio  
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2015
Mathematical Models and Methods in Applied Sciences

This paper is concerned with the mathematical analysis of a coupled elliptic–parabolic system modeling the interaction between the propagation of electric potential and subsequent deformation of the cardiac tissue. The problem consists in a reaction–diffusion system governing the dynamics of ionic quantities, intra- and extra-cellular potentials, and the linearized elasticity equations are adopted to describe the motion of an incompressible material. The coupling between muscle contraction, biochemical reactions and electric activity is introduced with a so-called active strain decomposition framework, where the material gradient of deformation is split into an active (electrophysiology-dependent) part and an elastic (passive) one. Under the assumption of linearized elastic behavior and a truncation of the updated nonlinear diffusivities, we prove existence of weak solutions to the underlying coupled reaction–diffusion system and uniqueness of regular solutions. The proof of existence is based on a combination of parabolic regularization, the Faedo–Galerkin method, and the monotonicity-compactness method of Lions. A finite element formulation is also introduced, for which we establish existence of discrete solutions and show convergence to a weak solution of the original problem. We close with a numerical example illustrating the convergence of the method and some features of the model.

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Type
research article
DOI
10.1142/S0218202515500244
Web of Science ID

WOS:000351125500006

Author(s)
Andreianov, Boris
Bendahmane, Mostafa
Quarteroni, Alfio  
Ruiz-Baier, Ricardo  
Date Issued

2015

Publisher

World Scientific Publ Co Pte Ltd

Published in
Mathematical Models and Methods in Applied Sciences
Volume

25

Issue

05

Start page

959

End page

993

Subjects

Electromechanical coupling

•

bidomain equations

•

bidomain equations

•

weak solutions

•

weak compactness method

•

weak–strong uniqueness

•

finite element approximation

•

convergence of approximations

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

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Available on Infoscience
May 27, 2015
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/114073
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