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  4. Enantioselective Rhodium(I)-Catalyzed [3+2] Annulations of Aromatic Ketimines Induced by Directed C?H Activations
 
research article

Enantioselective Rhodium(I)-Catalyzed [3+2] Annulations of Aromatic Ketimines Induced by Directed C?H Activations

Tran, Duc N.
•
Cramer, Nicolai  
2011
Angewandte Chemie International Edition

Triple selectivity: Highly substituted indenylamines can be obtained with high enantioselectivity by formal [3+2] additions of aryl ketimines with internal alkynes. These rhodium(I)-catalyzed processes proceed by selective C-H activation of one of the two arene substituents, regioselective carbometalation of the alkyne, and enantioselective addition across the imine. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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Type
research article
DOI
10.1002/anie.201105766
Web of Science ID

WOS:000297467100008

Author(s)
Tran, Duc N.
Cramer, Nicolai  
Date Issued

2011

Publisher

Wiley-VCH Verlag GmbH

Published in
Angewandte Chemie International Edition
Volume

50

Start page

11098

End page

11102

Subjects

alkynes

•

annulation

•

asymmetric catalysis

•

C?H activation

•

rhodium

•

H Bond Activation

•

Catalyzed Direct Arylation

•

Organic-Synthesis

•

Carbon-Hydrogen

•

Intermolecular Hydroacylation

•

Regioselective Synthesis

•

Benzoic-Acids

•

Alkynes

•

Functionalization

•

Cleavage

Editorial or Peer reviewed

REVIEWED

Written at

EPFL

EPFL units
LCSA  
Available on Infoscience
June 12, 2012
Use this identifier to reference this record
https://infoscience.epfl.ch/handle/20.500.14299/81630
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