Band Structure Determination In article number 2105426, Mirjana Dimitrievska, Anna Fontcuberta i Morral, and co-workers demonstrate how nanowires can be effectively used for direct determination of the band structure by means of valence electron energy-loss spectroscopy. This work opens the path for characterizing the band structure of new compounds in a non-destructive and facile manner, strengthening the route of new materials discovery.