Polymer or polycondensate based on peptide, linker and optionally other monomers and method for preparing the same
The present invention concerns a method for producing polymers suitable as carrier-free delivery system of bioactive molecules, in particular bioactive peptides. The method comprises the polycondensation of one or more different monomers, including monomers comprising the peptides, monomers comprising a cross-linker and, optionally, monomers comprising an adjuvant. The invention also relates to the polymers obtained by the method, which are suitable as medicaments, such as vaccines. In a particular embodiment, the bioactive peptide is a neoantigen and the polymer is used as a cancer vaccine.
68172078
Alternative title(s) : (de) Polymer oder polykondensat basierend auf einem peptid, einem linker und gegebenenfalls weiteren monomeren und verfahren zur herstellung davon (fr) Polymère ou polycondensat sur la base d'une peptide, d'une liaison et éventuellement autres monomères et son procédé de préparation
TTO:6.1971
| DOI | Country code | Kind code | Date issued |
WO2021053198 | WO | A1 | 2021-03-25 |
EP3795172 | EP | A1 | 2021-03-24 |