Lukinavičius, GražvydasBlaukopf, ClaudiaPershagen, EliasSchena, AlbertoReymond, LucDerivery, EmmanuelGonzalez-Gaitan, MarcosD’Este, ElisaHell, Stefan W.Wolfram Gerlich, DanielJohnsson, Kai2015-10-012015-10-012015-10-01201510.1038/ncomms9497https://infoscience.epfl.ch/handle/20.500.14299/119555WOS:000364928600001Cell-permeable DNA stains are popular markers in live-cell imaging. Currently used DNA stains for live-cell imaging are either toxic, require illumination with blue light or are not compatible with super-resolution microscopy, thereby limiting their utility. Here we describe a far-red DNA stain, SiR–Hoechst, which displays minimal toxicity, is applicable in different cell types and tissues, and is compatible with super-resolution microscopy. The combination of these properties makes this probe a powerful tool for live-cell imaging.text::journal::journal article::research article