Assessment of a sheep animal model to optimize photodynamic therapy with Foscan in the esophague

Glanzmann, Th.Zellweger, M.Borle, F.Conde, R.Radu, A.Ballini, J.Jaquet, Y.Pilloud, R.van den Bergh, H.Monnier, P.Wagnières, G.2007-07-202007-07-202007-07-20200910.1002/lsm.20844https://infoscience.epfl.ch/handle/20.500.14299/9707WOS:000271499900006Precursor lesions of oesophagus adenocarcinoma constitute a clinical dilemma. Photodynamic therapy (PDT) is an effective treatment for this indication, but it is difficult to optimise without an appropriate animal model. For this reason, we assessed the sheep model for PDT in the oesophagus with the photosensitiser meta-(tetra-hydroxyphenyl) chlorin (mTHPC).Photomedicine groupModelsAnimalPhotochemotherapyAssessment of a sheep animal model to optimize photodynamic therapy with Foscan in the esophaguetext::journal::journal article::research article