Thacher, Tyler NGambillara, VeronicaRiche, FabienneSilacci, PaoloStergiopulos, Nikosda Silva, Rafaela F2010-12-162010-12-162010-12-16200910.1016/j.atherosclerosis.2009.10.031https://infoscience.epfl.ch/handle/20.500.14299/62203WOS:00027708530001119945700Alterations of wall shear stress can predispose the endothelium to the development of atherosclerotic plaques. Ample evidence indicates that arginase expression and/or activity correlates with several risk factors for cardiovascular disease including atherosclerosis. We investigated the regulation of arginase pathway in response to distinct patterns of wall shear stress.ArginaseNitric oxideHemodynamic forcesWall shear stressOscillatory shear stressMechanotransductionAtherosclerosisPlaque-Prone HemodynamicsOxide-Mediated DilationNitric-OxideEndothelial DysfunctionCoronary ArteriolesCell-ProliferationCarotid ArteriesSmooth-MuscleUp-RegulationExpressionRegulation of arginase pathway in response to wall shear stresstext::journal::journal article::research article