Saqafi, SadeqHanahan, Douglas2022-12-012022-12-012022-12-012022https://infoscience.epfl.ch/handle/20.500.14299/192829The present invention relates to methods and compositions which provide a companion diagnostic for cancer therapy. A method for identifying and stratifying a patient or group of patients with cancer as (i) being high or low for FMRP activity, (ii) having a high or low risk prognosis, and/or (iii) being a responder or non-responder to cancer therapy, and/or (iv) having high or low immune cell infiltrated tumor.A pan-cancer classification based on fmrp pathway activity that informs differential prognosis and therapeutic responsespatentUS2024158871JP2024518129EP4341443AU2022277646CA3218895WO202224355082067720