Bartkowiak, ArturCanaple, LaurenceCeausoglu, IonNurdin, NathalieRenken, AndreasRindisbacher, LorenzWandrey, ChristineDesvergne, BeatriceHunkeler, David2006-02-272006-02-272006-02-27199910.1111/j.1749-6632.1999.tb08499.xhttps://infoscience.epfl.ch/handle/20.500.14299/226535WOS:000081586000011A new generation of microcapsules based on the use of oligomers which participate in polyelectrolyte complexation reactions has been developed. These freeze-thaw stable capsules have been applied as a bioartificial pancreas and have resulted in normoglycemia for periods of six months in concordant xenotransplantations. The new chem. permits the control of permeability and mech. properties over a wide range and can be adapted both to microcapsule and hollow fiber geometries rendering it a robust tool for encapsulation in general. Methods, and metrics, for the characterization of the mech. properties and permeability of microcapsules are presented. [on SciFinder (R)]text::journal::journal article::research article