Yao, BoWang, QianZhu, Jieping2020-07-092020-07-092020-07-092020-06-2910.1002/hlca.202000106https://infoscience.epfl.ch/handle/20.500.14299/169922WOS:000543806700001We report herein a synthesis of 5,6-diarylbenzo[a]carbazoles by a sequence of 6 pi-electrocyclization followed by beta-elimination. The highly functionalized 2,3-disubstituted indoles used for this cycloaromatization process are prepared by Pd-catalyzed cyclizative cross-coupling ofortho-alkynylanilines withortho-alkynylbenzamides. The combination of these two reactions allows us to develop a facile synthesis of benzo[a]carbazoles directly from two easily accessible internal alkynes without isolation of the indole intermediates.Chemistry, MultidisciplinaryChemistrybenzo[a]carbazoleindolescycloaromatizationvisible lightelectrocyclic reactionseliminationortho-alkynylanilinesh functionalizationpalladiumalkynesinsertiontext::journal::journal article::research article