Schlosser, ManfredSimig, Gyula2006-03-032006-03-032006-03-03199110.1016/0040-4039(91)85014-Vhttps://infoscience.epfl.ch/handle/20.500.14299/226882Butyllithium in Et2O smoothly metalates 3-MeOC6H4CH2CH2NHCOCMe3 at the ortho position flanked by the two substituents. Subsequent reaction with DMF followed by acid catalyzed cyclization and redn. gives 8-methoxy-1,2,3,4-tetrahydroisoquinoline (I). [on SciFinder (R)]Regiochemistry (of metalation of anisylpivaloylethylamine); Cyclocondensation reaction (intramol.of (pivaloylaminoethyl)anisaldehyde and synthesis of methoxyisoquinolines); Metalation (regioselectiveof anisylpivaloylethylamine in synthesis of methoxmethoxyisoquinoline; regioselective metalation methoxyphenylethylamine; isoquinoline methoxy8-Methoxyisoquinoline derivatives through ortho-selective metalation of 2-(3-methoxyphenyl)ethylaminetext::journal::journal article::research article