Zhu, YingdiJovic, MilicaLesch, AndreasLovey, Lysiane TissieresPrudent, MichelPick, HorstGirault, Hubert H.2018-12-202018-12-202018-12-202018-11-0510.1002/anie.201808666https://infoscience.epfl.ch/handle/20.500.14299/153120WOS:000452234400047A combination of an immuno-affinity enrichment strategy and sensitive amperometric read-out was implemented in a point-of-care platform intended for bacterial infection analysis. Bacterial cells, selectively captured and enriched from complex matrices through immuno-affinity, were detected by amperometric monitoring of the redox state of metabolic activity indicators, providing species identification and viable-cell quantification. The method was successfully employed for the diagnosis of bacterial infections including antimicrobial susceptibility testing with only several hours of total working time.Chemistry, MultidisciplinaryChemistrybacterial infectionsbiosensorselectrochemistrymetabolic activitypoint-of-care testingcarbon nanotubes electrodesblood-stream infectionstetrazolium saltsplasma-membranediagnosisresazurintoolstext::journal::journal article::research article