Nicolai, StefanoWaser, Jerome2011-12-162011-12-162011-12-16201110.1021/ol2029383https://infoscience.epfl.ch/handle/20.500.14299/73215WOS:000297274700048The first Pd(0)-catalyzed intramolecular oxy- and aminoalkynylation of nonactivated olefins is reported. The reaction gives access to important tetrahydrofuran and pyrrolidine heterocycles with high diastereoselectivity. The unique synthetic potential of acetylenes is further exploited to access key building blocks for the synthesis of bioactive natural products.Palladium-Catalyzed SynthesisC-H BondsStereoselective-SynthesisTerminal AlkynesCarboamination ReactionsAminoalkynylationOrganic SynthesisHeterocyclesPd(0)-Catalyzed Oxy- and Aminoalkynylation of Olefins for the Synthesis of Tetrahydrofurans and Pyrrolidinestext::journal::journal article::research article