Fajas, LDebril, M BAuwerx, J2009-04-022009-04-022009-04-022001https://infoscience.epfl.ch/handle/20.500.14299/3680611383325The peroxisome proliferator-activated receptor gamma is a nuclear hormone receptor playing a crucial role in adipogenesis and insulin sensitization. Prostaglandin J2 derivatives and the antidiabetic thiazolidinediones are its respective natural and synthetic ligands. The RXR/PPAR gamma heterodimer has also been reported to have important immunomodulatory activities and its pleiotropic functions suggest wide-ranging medical implications.Thiazolidinedionestext::journal::journal article::review article