Drouet, FleurMasson, GéraldineZhu, Jieping2013-06-072013-06-072013-06-07201310.1021/ol401181ahttps://infoscience.epfl.ch/handle/20.500.14299/92606WOS:000320298900073A new, simple, and efficient procedure for the one-pot Ugi four-component reaction of alcohols instead of aldehydes is described. Using a stoichiometric amount of IBX or only 1-2% of sodium 2-iodobenzenesulfonate in the presence of Oxone, a wide range of primary alcohols were oxidized to the aldehyde that were directly engaged in the Ugi four-component reaction to afford alpha-acetamidoamides in good to excellent yields.text::journal::journal article::research article