Activation of a C(sp3)H Bond by a Transient s-Alkylpalladium(II) Complex: Synthesis of Spirooxindoles Through a Palladium-Catalyzed Domino Carbopalladation/C(sp3)C(sp3) Bond-Forming Process

Piou, TiffanyNeuville, LucZhu, Jieping2012-11-092012-11-092012-11-09201210.1002/anie.201206267https://infoscience.epfl.ch/handle/20.500.14299/86806WOS:000310875700028Heck shortens the distance. Palladium-catalyzed activation of C(sp3)-H bond by a σ-alkyl Pd(II) complex generated in situ from a remote arylhalide function is developed. The novel domino carbopalladation/C(sp3)-C(sp3) bond forming process allowed a rapid access to biologically relevant spirooxindoles.C-H activationdomino reactionheterocyclespalladiumspirooxindolesActivation of a C(sp3)H Bond by a Transient s-Alkylpalladium(II) Complex: Synthesis of Spirooxindoles Through a Palladium-Catalyzed Domino Carbopalladation/C(sp3)C(sp3) Bond-Forming Processtext::journal::journal article::research article