4-Nitrophenyltriflate and 4-Nitrophenylnonaflate as New Perfluoroalkanesulfonyl Transfer Agents: Experimental and Computational Studies

Neuville, LucBigot, AntonyDau, Marie Elise Tran HuuZhu, Jieping2010-11-252010-11-252010-11-25199910.1021/jo990559lhttps://infoscience.epfl.ch/handle/20.500.14299/585264-Nitrophenyl triflate (1) as well as 4-nitrophenyl nonaflate (2) are excellent perfluoroalkanesulfonyl transfer agents. An important feature of the present method is its chemoselectivity. The aliph. hydroxy function was inert under the reaction conditions studied , and consequently phenols can be selectively triflated in the presence of alc. Frontier MO calcns. were used to rationalize the exptl. results. [on SciFinder (R)]FMO (4-nitrophenyltriflate and 4-nitrophenylnonaflate as new perfluoroalkanesulfonyl transfer agents)nitrophenyl triflate perfluoroalkanesulfonyl transfer agent4-Nitrophenyltriflate and 4-Nitrophenylnonaflate as New Perfluoroalkanesulfonyl Transfer Agents: Experimental and Computational Studiestext::journal::journal article::research article