Bikia, VasilikiStergiopulos, Nikolaos2024-03-042024-03-042024-03-042024https://infoscience.epfl.ch/handle/20.500.14299/205754[0054] Methods are provided for estimating key reliably and accurately predicting cardiac output using a limited set of non-invasively monitored physiologic inputs, and a calibrated one- dimensional arterial tree model, a database of synthetic data generated from such a model, and an artificial intelligence module. Systems for estimating CO based on non-invasively measured physiologic inputs also are provided that may be implemented without the need for extensive real-time computing resources.patentWO202403379387760651