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LaszloJones, MatthewJung, Andreas WernerKhatiwada, AjeetaMiller, David HarryNeumeister, NorbertPeng, Cheng-ChiehQiu, HaoSchulte, Jan-FrederikSun, JianWang, FuqiangXiao, RuiXie, WeiCheng, TongguangParashar, NeetiStupak, JohnChen, ZhenyuEcklund, Karl MatthewFreed, SarahGeurts, Frank JMGuilbaud, MaximeKilpatrick, MatthewLi, WeiMichlin, BenjaminPadley, Brian PaulRoberts, JayRorie, JamalShi, WeiTu, ZhoudunmingZabel, JamesZhang, AoboBodek, Ariede Barbaro, PawelDemina, ReginaDuh, Yi-tingFerbel, ThomasGalanti, MarioGarcia-Bellido, AranHan, JiyeonHindrichs, OttoKhukhunaishvili, AlekoLo, Kin HoTan, PingVerzetti, MauroCiesielski, RobertGoulianos, KonstantinMesropian, ChristinaAgapitos, AntonisChou, John PaulGershtein, YuriGómez Espinosa, Tirso AlejandroHalkiadakis, EvaHeindl, MaximilianHughes, ElliotKaplan, StevenKunnawalkam Elayavalli, RaghavKyriacou, SavvasLath, AmitabhMontalvo, RoyNash, KevinOsherson, MarcSaka, HalilSalur, SevilSchnetzer, SteveSheffield, DavidSomalwar, SunilStone, RobertThomas, ScottThomassen, PeterWalker, MatthewDelannoy, Andrés GHeideman, JosephRiley, GrantRose, KeithSpanier, StefanThapa, KrishnaBouhali, OthmaneCastaneda Hernandez, AlfredoCelik, AliDalchenko, MykhailoDe Mattia, MarcoDelgado, AndreaDildick, SvenEusebi, RicardoGilmore, JasonHuang, TaoKamon, TerukiMueller, RyanPakhotin, YuriyPatel, RishiPerloff, AlexxPerniè, LucaRathjens, DenisSafonov, AlexeiTatarinov, AysenAkchurin, NuralDamgov, JordanDe Guio, FedericoDudero, Phillip RussellFaulkner, JamesGurpinar, EmineKunori, ShuichiLamichhane, KamalLee, Sung WonLibeiro, TerenceMengke, TieligeMuthumuni, SamilaPeltola, TimoUndleeb, SonainaVolobouev, IgorWang, ZhixingGreene, SentaGurrola, AlfredoJanjam, RaviJohns, WillardMaguire, CharlesMelo, AndrewNi, HongPadeken, KlaasSheldon, PaulTuo, ShengquanVelkovska, JuliaXu, QiaoArenton, Michael WayneBarria, PatriziaCox, BradleyHirosky, RobertJoyce, MatthewLedovskoy, AlexanderLi, HengneNeu, ChristopherSinthuprasith, TutanonWang, YanchuWolfe, EvanXia, FanHarr, RobertKarchin, Paul EdmundPoudyal, NabinSturdy, JaredThapa, PrakashZaleski, ShawnBrodski, MichaelBuchanan, JamesCaillol, CécileCarlsmith, DuncanDasu, SridharaDodd, LauraDuric, SenkaGomber, BhawnaGrothe, MonikaHerndon, MatthewHervé, AlainHussain, UsamaKlabbers, PamelaLanaro, ArmandoLevine, AaronLong, KennethLoveless, RichardRekovic, VladimirRuggles, TylerSavin, AlexanderSmith, NicholasSmith, Wesley HTaylor, DevinWoods, Nathaniel2020-02-172020-02-172020-02-172018-02-1910.1140/epjc/s10052-018-5607-5https://infoscience.epfl.ch/handle/20.500.14299/1657721710.10614A search for standard model production of four top quarks ( $\mathrm {t}\overline{\mathrm {t}} \mathrm {t}\overline{\mathrm {t}} $ ) is reported using events containing at least three leptons ( $\mathrm {e}, \mathrm {\mu }$ ) or a same-sign lepton pair. The events are produced in proton–proton collisions at a center-of-mass energy of 13 $\,\text {TeV}$ at the LHC, and the data sample, recorded in 2016, corresponds to an integrated luminosity of 35.9 $\,\text {fb}^{-1}$ . Jet multiplicity and flavor are used to enhance signal sensitivity, and dedicated control regions are used to constrain the dominant backgrounds. The observed and expected signal significances are, respectively, 1.6 and 1.0 standard deviations, and the $\mathrm {t}\overline{\mathrm {t}} \mathrm {t}\overline{\mathrm {t}} $ cross section is measured to be $16.9^{+13.8-11.4}$ $\,\text {fb}$ , in agreement with next-to-leading-order standard model predictions. These results are also used to constrain the Yukawa coupling between the top quark and the Higgs boson to be less than 2.1 times its expected standard model value at 95% confidence level.p p: scatteringp p: colliding beamstop: multiple productionW: leptonic decaychannel cross section: measuredjet: multiplicitycoupling: Yukawaquantum chromodynamics: perturbation theoryperturbation theory: higher-orderhigher-order: 1same signfinal state: ((n)jet 3lepton)Higgs particle: couplingCERN LHC Collsensitivitybackgroundflavorexperimental results13000 GeV-cmstext::journal::journal article::research article