Geueke, BirgitMiska, Milena E.Poiger, ThomasRentsch, DanielLal, RupHolliger, ChristofKohler, Hans-Peter E.2013-11-042013-11-042013-11-04201310.1128/Aem.01770-13https://infoscience.epfl.ch/handle/20.500.14299/96595WOS:000324176900046delta-Hexachlorocyclohexane (delta-HCH), one of the prevalent isomers of technical HCH, was enantioselectively dehydrochlorinated by the dehydrochlorinases LinA1 and LinA2 from Sphingobium indicum B90A to the very same delta-pentachlorocyclohexene enantiomer. Racemic delta-pentachlorocyclohexene, however, was transformed with opposite enantioselectivities by the two enzymes. A transformation pathway based on an anti-1,2-elimination, followed by a syn-1,4-elimination and a subsequent syn-1,2-elimination is postulated.Biodegradationpesticideslindanetext::journal::journal article::research article