Mariello, MassimoRosenthal, James D.Cecchetti, FrancescoGao, MingxiangSkrivervik, AnjaLeterrier, YvesLacour, Stéphanie2024-11-212024-11-212024-11-212024-08-2810.1038/s41467-024-51247-3https://infoscience.epfl.ch/handle/20.500.14299/242103Long-term bioelectronic implants require stable, hermetic encapsulation. Water and ion ingress are challenging to quantify, especially in miniaturized microsystems and over time. We propose a wireless and battery-free flexible platform leveraging backscatter communication and magnesium (Mg)-based microsensors. Water permeation through the encapsulation induces corrosion of the Mg resistive sensor thereby shifting the oscillation frequency of the sensing circuit. Experimental in vitro and in-tissue characterization provides information on the operation of the platform and demonstrates the robustness and accuracy of this promising method, revealing its significance for insitu real-time monitoring of implanted bioelectronics.entext::revue::article de revue::article de revue scientifique