A Pyridinol Acyl Cofactor in the Active Site of [Fe]-hydrogenase Evidenced by the Reactivity of Model Complexes

Hu, BowenChen, DafaHu, Xile2012-07-192012-07-192012-07-19201210.1002/chem.201201954https://infoscience.epfl.ch/handle/20.500.14299/83995WOS:000308313100003The decomposition reaction of a water-soluble complex (see scheme; 1) in H2O confirms the existence of a unique bidentate pyridinol cofactor in [Fe]-hydrogenase. This unique moiety is confirmed for the first time by the decomposition of a well-defined model complex containing a pyridinyl methyl acyl ligand.enzyme modelscofactorshydrogenaseironA Pyridinol Acyl Cofactor in the Active Site of [Fe]-hydrogenase Evidenced by the Reactivity of Model Complexestext::journal::journal article::research article