Agoshkov, ValeryQuarteroni, AlfioRozza, Gianluigi2007-04-242007-04-242007-04-24200610.1137/040613287https://infoscience.epfl.ch/handle/20.500.14299/5431WOS:0002360998000208238We present a new approach in the study of aorto-coronaric bypass anastomoses configurations based on small perturbation theory. The theory of optimal control based on adjoint formulation is applied in order to optimize the shape of the zone of the incoming branch of the bypass (the toe) into the coronary. The aim is to provide design indications in the perspective of future development for prosthetic bypasses.optimal controlshape optimizationsmall perturbation theoryfinite elementshaemodynamicsaorto-coronaric bypass anastomosesdesign of improved medical devicesShape design in aorto-coronaric bypass anastomoses using perturbation theorytext::journal::journal article::research article