Jia, YanxingBois-Choussy, MicheleZhu, Jieping2010-11-252010-11-252010-11-25200810.1002/anie.200800599https://infoscience.epfl.ch/handle/20.500.14299/58416Atropisomers as well as CC2 epimers of complestatin and chloropeptin I are readily synthesized through an intramol. SNAr reaction and the Suzuki-Miyaura reaction. The abs. configuration of amino acid N-methyl-2-(3,5-dichloro-4-hydroxyphenyl)glycine was found to det. the atropselectivity of the aryl-aryl bond-forming reaction. [on SciFinder (R)]Suzuki coupling reaction (-Miyauraintramol.; total synthesis of diastereomers of complestatin and chloropeptin with atropstereoselective intramol. Suzuki-Miyaura reaction as a key step); Substitution reaction (arom.intramol.; total synthesis of diastereomers of complestatin and chloropeptin with atropstereoselective intramol. Suzuki-Miyaura reaction as a key step); Macrocyclic compounds Role: SPN (Synthetic preparation)PREP (Preparation) (peptidyl-; total synthesis of diastereomers of complestatin and chloropeptin with atropstereoselective intramol. Suzuki-Miyaura reaction as a key step); Atropisomers; Chirality; Stereoselective synthesis (total synthesis of diastereomers of complestatin and chloropeptin with atropstereoselective intramol. Suzuki-Miyaura reaction as a key step); Peptides Role: RCT (Reactant)SPN (Synthetic preparation)PREP (Preparation)RACT (Reactant or reagent) (total synthesis of diastereomers of complestatin and chloropeptin with atropstereoselective intramol. Suzuki-Miyaura reaction as a key step)complestatin chloropeptin diastereomer macrocycle atropisomer prepn Suzuki Miyaura reactiontext::journal::journal article::research article