Hu, Xile2011-07-222011-07-222011-07-22201110.1039/C1SC00368Bhttps://infoscience.epfl.ch/handle/20.500.14299/69730WOS:000294503900001Cross coupling of non-activated alkyl halides is a potentially transformative methodology in organic synthesis. Herein we review the recent development of nickel-catalyzed coupling of non-activated alkyl halides. The current understanding of the mechanism of these coupling reactions is highlighted. As the mechanism is ligand-dependant, the perspective is organized according to the types of ligands employed in the catalysis.text::journal::journal article::research article