Wu, Yan-ChaoZhu, Jieping2010-11-252010-11-252010-11-25200910.1021/ol9024919https://infoscience.epfl.ch/handle/20.500.14299/58390Using ring opening and Pictet-Spengler reactions of nonracemic amino acid-derived aziridine building blocks as key steps, (-)-renieramycin M I [R = (Z)-MeCH:CMeCO; R = NC; R1 = H], (-)-renieramycin G I [R = (Z)-MeCH:CMeCO; RR1 = O], (-)-jorumycin I (R = MeCO; R1 = HO; R2 = H), and (-)-jorunnamycin A I (R = H; R1 = NC; R2 = H) are prepd. convergently. [on SciFinder (R)]Heterocyclic compounds Role: RCT (Reactant)SPN (Synthetic preparation)PREP (Preparation)RACT (Reactant or reagent) (nitrogenaziridines; stereoselective prepn. of (-)-renieramycins G and M(-)-jorumycinand (-)-jorunnamycin A using ring opening and Pictet-Spengler reactions of nonracemic amino acid-derived aziridine building blocks as key steps); Stereoselective synthesis (stereoselective prepn. of (-)-renieramycins G and M(-)-jorumycinand (-)-jorunnamycin A using ring opening and Pictet-Spengler reactions of nonracemic amino acid-derived aziridine building blocks as key steps); Pictet-Spengler cyclocondensation reaction; Ring opening (stereoselective; stereoselective prepn. of (-)-renieramycins G and M(-)-jorumycinand (-)-jorunnamycin A using ring opening and Pictet-Spengler reactions of nonracemic amino acid-derived aziridine building blocks as key steps)renieramycin G M stereoselective nonracemic prepn; jorumycin stereoselective nonracemic prepn; jorunnamycin A stereoselective nonracemic prepn; ring opening reaction amino acid derived aziridine prepn renieramycin; Pictet Spengler reaction amino acid derived aziridine prepn renieramycintext::journal::journal article::research article