Casulli, Maria AntoniettaTaurino, IreneHashimoto, TakeshiCarrara, SandroHayashita, Takashi2021-05-082021-05-082021-05-082021-04-1910.1021/acsabm.1c00166https://infoscience.epfl.ch/handle/20.500.14299/177901WOS:000642377800012Electrochemical detection based on cyclodextrin supramolecular complexes is founded on the competitive binding between electroactive probes and target molecules. This limits their versatility to be used for sensing a broad range of metabolites. In this work, we demonstrate the significant role of zinc ions as well as of beta-cyclodextrins modified with dipicolylamine and of a phenylboronic acid-modified ferrocene probe to address a selective electrochemical detection of adenosin triphosphate (ATP). Our findings will definitively have an impact in oncological point-of-care systems, since a high level of extracellular ATP reveals the inflammatory response due to chemotherapeutic treatments.Nanoscience & NanotechnologyMaterials Science, BiomaterialsScience & Technology - Other TopicsMaterials Sciencesupramolecular complexesferrocenedipicolylaminecyclodextrinselectrochemical detectionadenosin triphosphateatpplatformacidtext::journal::journal article::research article