Gerfaud, ThibaudNeuville, LucZhu, Jieping2010-11-252010-11-252010-11-25200910.1002/anie.200804683https://infoscience.epfl.ch/handle/20.500.14299/58395A palladium-catalyzed domino aminopalladation/C-H functionalization sequence has been developed, and provides access to functionalized phenanthridines and isoquinolines. The use of butyronitrile as the solvent is determinant to the success of the domino process. [on SciFinder (R)]Ketones Role: RCT (Reactant)RACT (Reactant or reagent) (aryl; prepn. of pentafluorobenzoyl oximes via condensation of ketones with hydroxyamine followed by esterification with pentafluorobenzoyl chlorideand their use in prepn. of phenanthridines and isoquinolines); Alkynes; Aromatic hydrocarbons Role: RCT (Reactant)SPN (Synthetic preparation)PREP (Preparation)RACT (Reactant or reagent) (arynes; prepn. of phenanthridines and isoquinolines via palladium-catalyzed annulation of acyloximes with in situ generated benzyne from silylphenyl triflates); Cyclization (prepn. of phenanthridines and isoquinolines via palladium-catalyzed annulation of acyloximes with in situ generated benzyne from silylphenyl triflates)phenanthridine prepn; isoquinoline prepn; acyloxime prepn aryne annulation palladiumtext::journal::journal article::research article