Kobel, StefanCosson, SteffenLutolf, Matthias2008-11-212008-11-212008https://infoscience.epfl.ch/handle/20.500.14299/31613Extra-cellular matrix (ECM) tethered morphogen gradients play an important role in tissue development and regeneration. There is currently only a limited set of model systems which can mimic these gradients in an artificial ECM-like environment. We have developed such a system that is able to stably immobilize a microfluidics-generated protein gradient on a poly(ethylene) glycol (PEG) hydrogel. After patterning, the hydrogel can be released from the chip and be directly used for cell culture.GradientHydrogelPoly(ethylene) GlycolCell AssayMicrofluidics-generated immobilized biomolecule gradients on hydrogelstext::conference output::conference proceedings::conference paper