Moret, Marc-EtienneTapavicza, EnricoGuidoni, LeonardoRohrig, Ute F.Sulpizi, MarialoreTavernelli, IvanoRothlisberger, Ursula2006-02-272006-02-272006-02-27200510.2533/000942905777676128https://infoscience.epfl.ch/handle/20.500.14299/226230WOS:000231615300004The combination of time-dependent d. functional theory (TDDFT) for the description of excited states with a hybrid quantum mechanics/mol. mechanics (QM/MM) approach enables the study of photochem. processes in complex environments. Here, we present a short overview of recent applications of TDDFT/MM approaches to a variety of systems including studies of the optical properties of prototypical org. and inorg. mols. in gas phase and soln., photoinduced electron transfer reactions in donor-bridge-acceptor complexes, and in situ investigations of the mol. mechanisms of photoactive proteins. The application of TDDFT/MM techniques to a wide range of systems enables an assessment of the current performance and limitations of these methods for the characterization of photochem. processes in complex systems. [on SciFinder (R)]text::journal::journal article::research article