Optimizing the relaxivity of Gd(III) complexes appended to InP/ZnS quantum dots by linker tuning

Stasiuk, Graeme J.Tamang, SudarsanImbert, DanielGateau, ChristelleReiss, PeterFries, PascalMazzanti, Marinella2014-11-072014-11-072014-11-07201310.1039/c3dt50774bhttps://infoscience.epfl.ch/handle/20.500.14299/108509WOS:000319286300006Three bimodal MRI/optical nanosized contrast agents with high per-nanoparticle relaxivity (up to 2523 mM-1 s-1 at 35 MHz and 932 mM-1 s-1 at 200 MHz) have been prepared connecting up to 115 tris-aqua GdIII complexes to fluorescent non-toxic InP/ZnS quantum dots. The structure of the linker has an important effect on the relaxivity of the final multimeric contrast agent. © 2013 The Royal Society of Chemistry.Optimizing the relaxivity of Gd(III) complexes appended to InP/ZnS quantum dots by linker tuningtext::journal::journal article::research article