Gamby, JAbid, JPAnsermet, JPGirault, HH2006-08-292006-08-292006-08-29200610.1021/ac060479zhttps://infoscience.epfl.ch/handle/20.500.14299/233889WOS:000239393100016Here we present the detection of ultralow concentrations of biomolecules in a device made from a polycarbonate membrane containing a network of gold nanowires and using a “contactless” impedance tomoscopy technique. The sensor comprises a thin dielectric layer with two parallel band electrodes on the one side and a microchannel containing gold nanowires onto which the adsorption of antibodies occurs. Upon applying a highfrequency ac voltage between the two electrodes, the adsorption process occurring at the surface of the gold nanowires can be followed through contactless impedance measurements. The configuration allows the real-time detection of biomolecules with a bulk concentration in the picomolar range.text::journal::journal article::research article