Barton, Derek H. R.Zhu, Jieping2010-11-252010-11-252010-11-25199210.1016/S0040-4020(01)86582-0https://infoscience.epfl.ch/handle/20.500.14299/58580Regioselective nucleophilic ring opening of isopropylidene ketals of simple diols or sugars, e.g. I (R = Ac, CH2Ph), by AlMe3 gave the corresponding II (R = H, CH2PH). This reagent offers a new method for selective monoprotection of 1,2-diols. [on SciFinder (R)]Regiochemistry (of ring cleavage of isopropylidene ketals)Ring cleavage (regioselective of isopropylidene ketals with trimethylaluminum)regioselective nucleophilic ring cleavage isopropylidene ketalalditol isopropylidene ketal regioselective ring cleavageAn efficient procedure for the regioselective monoprotection of 1,2-diolstext::journal::journal article::research article