Jiang, JingjingMata, Aldo di CostanzoLindner, ScottCharbon, EdoardoWolf, MartinKalyanov, Alexander2020-10-292020-10-292020-10-292020-10-0110.1364/BOE.399387https://infoscience.epfl.ch/handle/20.500.14299/172863WOS:000577572500007In many clinical applications it is relevant to observe dynamic changes in oxygenation. Therefore the ability of dynamic imaging with time domain (TD) near-infrared optical tomography (NIROT) will be important. But fast imaging is a challenge. The data acquisition of our handheld TD NIROT system based on single photon avalanche diode (SPAD) camera and I 1 light sources was consequently accelerated. We tested the system on a diffusive medium simulating tissue with a moving object embedded. With 3D image reconstruction, the moving object was correctly located using only 0.2 s exposure time per source. (C) 2020 Optical Society of America under the terms of the OSA Open Access Publishing AgreementBiochemical Research MethodsOpticsRadiology, Nuclear Medicine & Medical ImagingBiochemistry & Molecular Biologytext::journal::journal article::research article