Seiser, TobiasCramer, Nicolai2011-08-172011-08-172011-08-17200810.1002/anie.200804281https://infoscience.epfl.ch/handle/20.500.14299/70150Chiral rhodium(I) complexes activate allenyl tert-cyclobutanols efficiently through enantioselective insertion into a C-C σ bond of the cyclobutane. Ring expansion by this method produced cyclohexenones with quaternary stereogenic centers with excellent enantioselectivity. The catalyst loading can be decreased to just 0.1 mol% in rhodium.cyclohexenone asym prepnallenyl cyclobutanol enantioselective desymmetrization rhodium catalystcarbon carbon bond activation insertion ring expansion rearrangementEnantioselective C-C bond activation of allenyl cyclobutanes: access to cyclohexenones with quaternary stereogenic centerstext::journal::journal article::research article