Cantó, CarlesAuwerx, Johan2009-04-022009-04-022009-04-02200810.1016/j.devcel.2008.04.012https://infoscience.epfl.ch/handle/20.500.14299/36797WOS:0002558988000051243718477447The two metabolic sensors AMPK and SIRT1 take center stage as Fulco et al. reveal, in this issue of Developmental Cell, the signaling mechanism by which low glucose prevents the correct development of the myogenic program. These observations may hold some therapeutic promise against muscle wasting.LongevityGlucose restriction: longevity SIRTainly, but without building muscle?text::journal::journal article::review article